Transgenic Platforms
for Antibody Generation
World-class transgenic animals for unparalleled discovery of naturally optimized human antibodies®
Our proprietary transgenic animals, including OmniRat®, OmniChicken® and OmniMouse® have been genetically modified to generate antibodies with human sequences to streamline the development of human therapeutic candidates. OmniFlic® and OmniClic® are fixed or common light-chain rats and chickens, respectively, designed to facilitate the discovery of bispecific antibodies. OmniTaur™ provides cow-inspired antibodies with unique structural characteristics for challenging targets. OmnidAb®, is an in vivo platform for the discovery of single domain antibodies based upon a human VH scaffold that affinity matures in a chicken host environment to provide a functionally diverse immune repertoire unavailable from mammalian systems.
Our expertise in developing transgenic animal platforms ensures that they have the most flexible options for discovering high-quality antibody leads. We work closely with our partners’ teams to create effective transgenic animal models for human diseases to customize and optimize the process for every campaign. Get in touch with us today to learn more about our full capabilities.
Discover OmniAb’s suite of transgenic animals
OmniMouse delivers fully human antibodies using standard mouse-based protocols.
OmniChicken is optimized for human antibody research.
A human VH domain benefiting from being generated in a chicken host. Discover OmnidAb.
