High throughput single B-cell screening for monoclonal antibodies

Large repertoires of human sequence antibodies can present a challenge in identifying the antibodies with the most optimal candidate drug profiles from millions of possibilities. OmniAb’s robust high throughput single B-cell screening technologies enable deep searches into immune repertoires to identify unique antibodies with superior target profile. Discover GEM and xPloration^®, OmniAb’s proprietary screening technologies that allow high throughput phenotypic profiling of antibodies produced by single primary B cells and rapid cloning of their variable regions. These parallel workflows provide efficient processes to retrieve large panels of hits even against difficult targets such as GPCRs or ion channels.